Dr. V Sabareesh

Designation : Assistant Professor Senior Grade 1
School / Centre : Centre for Bio Separation Technology
Department : Biotechnology

Educational Details

Indian Institute of Science, Bengaluru, India

Molecular Biophysics -Thesis title: Mass spectrometric sequencing of acyclic and cyclic peptides
Graduated in 2008

Pondicherry University, Puducherry

M.Sc. (5 Year Integrated)
Graduated in 2001

Post Doctoral Experiences

1. 26/02/2008-25/02/2009; Prof. Simon J. Gaskell’s Group, Michael Barber Centre for Mass Spectrometry, University of Manchester, United Kingdom. Mass spectrometry-based proteomics of pooled liver microsomes 2. 10/05/2009-10/07/2010; Prof. Dipankar Chatterji’s Group (Molecular Biophysics Unit, IISc, Bengaluru), Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru, India. Application of mass spectrometry-based bottom-up proteomic approach involving combined collision-induced dissociation (CID) and electron transfer dissociation (ETD) tandem mass spectrometric methods. 3. 10/07/2010-15/01/2013; CSIR -Institute of Genomics and Integrative Biology (IGIB), New Delhi, India. Applications of mass spectrometry for chemical biology involving studies on peptides, lipids, cyclic dinucleotides and for bottom-up proteomic approach.

Research Details

Areas of Specialization
  • 2. Biomolecular Mass Spectrometry
  • Peptide
  • Protein & Lipid Mass Spectrometry
  • 3.  Applied Chromatography
  • in particular reverse-phase HPLC
  • 4. Applications of LC-MS
  • particularly electrospray ionization (ESI) 6. Applications of matrix-assisted laser desorption/ionization – MS

: 12
: 14

Ongoing Funded Project Details

Title Funding Agency
Immunometabolomics in the quest for comprehending protection and pathogenesis in tuberculosis. Role: Co-PI; 02/2023-Present; Fund: Rs. 27.91 Lakhs ICMR, India
Inhibitory effects of linear alkyl benzene sulfonates, mono-n-octyl phthalate and di-n-octyl phthalate on Mycobacterium avium subspecies paratuberculosis, a major animal and human pathogen. Role: Co-PI. 2022-23; Rs. 50,000/- VIT Seed Grant

Completed Funded Project Details

Title Funding Agency
Evaluation of applicability of different arginine-modifying tags for middle-down proteomics by electrospray mass spectrometry. Role: PI; 11/2014 - 11/2017; Fund: Rs. 21 Lakhs SERB, India (Start-Up Research Grant for Young scientists)
Ligand targeted PROTAC Conjugates Chemically Induced Degradation of Disease-causing by a PROteolysis Targeting chimeras PROTACs coupled with tumor targeting ligands. Role: Co-PI. 12/2020 - 12/2023; Fund: Rs. 36.048 Lakhs SERB, India (Core Research Grant)
Inhibitory effects of linear alkyl benzene sulfonates, mono-n-octyl phthalate and di-n-octyl phthalate on Mycobacterium avium subspecies paratuberculosis, a major animal and human pathogen. Role: Co-PI. 2021-22; Rs. 1 Lakh. VIT Seed Grant
Identification of DPP-IV inhibitors from the milk proteins of donkey and buffalo. Role: PI. 2020-21; Rs. 75,000/- VIT Seed Grant

Books / Book Chapters Published Details

Title Publisher Published Year
Chapter title: Research contributions from India on membrane-modifying peptides: Motivations from Fungal Peptaibiotics. Book Title: Progress in Mycology - Biology and Biotechnological Applications. Editors: Tulasi Satyanarayana, Sunil Kumar Deshmukh, Mukund V. Deshpande. ISBN No. 978-981-16-3306-5, ISBN No. 978-981-16-3307-2 (e-book) Springer, Singapore 2021
Chapter title: A Glimpse into Peptidomic Approach Book Title: Integrated Omics Approaches to Infectious Diseases. Editors: S. Hameed, Z. Fatima. ISBN No. 978-981-16-0690-8, ISBN No. 978-981-16-0691-5 (online) Springer, Singapore 2021
Chapter title: A Bird’s-Eye View of Fungal Peptides Book title: Fungi and Fungal Products in Human Welfare and Biotechnology. Editors: Tulasi Satyanarayana, Sunil Kumar Deshmukh. ISBN No. 978-981-19-8852-3, ISBN No. 978-981-19-8853-0 (online) Springer, Singapore 2023
Chapter title: A Brief Insight into Peptide and Non-Peptide Drugs of Fungal Origin. Book title: Fungi Bioactive Metabolites. Editors: Deshmukh, S.K., Takahashi, J.A., Saxena, S. ISBN No. 978-981-99-5695-1, ISBN No. 978-981-99-5696-8 (online) Springer, Singapore 2024

Awards & Recognitions Details

  • Visiting Scientist Fellowship 2017-2018 of Indian National Science Academy (INSA), New Delhi. Availing this fellowship, visited Prof. N. Srinivasan’s Lab in Molecular Biophysics Unit (MBU), IISc, Bengaluru, to learn molecular dynamics simulations, during December 2017 - January 2018 (One Month).
  • “Young Mass Spectrometrist Award” conferred by Indian Society for Mass Spectrometry (ISMAS) in 2013.
  • Received Prof. B. H. Iyer Medal in March 2008 for Best Ph.D thesis within MBU, IISc, Bengaluru for the academic year 2007-08.

Other Information